Description

Ceftazidime Sodium CAS NO 73547-61-2 is a third-generation, broad-spectrum cephalosporin antibiotic in its sodium salt form, designed for enhanced stability and solubility. It is a critical active pharmaceutical ingredient (API) valued for its potent activity against a wide range of Gram-negative bacteria, including Pseudomonas aeruginosa. This product is essential for pharmaceutical manufacturers and compounding facilities producing sterile injectable formulations for the treatment of serious infections in hospital and clinical settings.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of sterile injectable antibiotic formulations.
• Hospital & Clinical Use: Formulated into solutions for intravenous (IV) or intramuscular (IM) administration to treat severe infections like pneumonia, septicemia, and meningitis.
• Anti-Pseudomonal Therapy: A key therapeutic agent for infections caused by Pseudomonas aeruginosa, a common and challenging pathogen in healthcare settings.
• Complicated Urinary Tract Infections (cUTI): Used in formulations targeting difficult-to-treat urinary tract infections.
• Complicated Intra-Abdominal Infections (cIAI): Employed in combination therapies for abdominal infections.
• Bone and Joint Infections: Utilized in the management of osteomyelitis and other deep-seated bacterial infections.
• Research & Development: Serves as a reference standard and raw material in microbiological research and new drug development studies.

Basic Information

Product Name	Ceftazidime Sodium
CAS No.	73547-61-2
Molecular Formula	C22H21N6O7S2 • xNa
Molecular Weight	546.56 g/mol (for free acid, C22H22N6O7S2)
Synonyms	Ceftazidime Sodium Salt; Ceftazidime Na; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(1-carboxy-1-methylethoxy)imino]acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium; GR-20263; Fortaz; Tazicef; Tazidime; Ceptaz
EINECS	Contact for details

Quality Control

Our Ceftazidime Sodium is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including compliance with relevant pharmacopoeial monographs (e.g., USP, EP). A comprehensive Certificate of Analysis (COA) documenting identity, purity, potency, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	96.0% - 102.0% (on anhydrous basis)
pH (10% solution)	3.5 - 6.0
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity: ≤ 1.0% Total impurities: ≤ 3.0%
Sterility (for sterile grade)	Sterile
Bacterial Endotoxins	< 0.10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.