Description

n-Cbz-(R)-2-Amino-1-Butanol is a chiral, N-protected amino alcohol building block of significant importance in synthetic organic chemistry. This compound is a key intermediate for the stereoselective synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily utilized by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), peptide mimetics, and chiral catalysts.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure drugs, particularly β-blockers, antiviral agents, and other bioactive molecules.
• Peptide Chemistry: Serves as a protected amino alcohol component in the synthesis of peptidomimetics and modified peptide sequences.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective transformations.
• Agrochemical Synthesis: Employed in the production of chiral herbicides, fungicides, and plant growth regulators.
• Material Science: A building block for chiral polymers, liquid crystals, and advanced functional materials.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in medicinal and process chemistry.

Basic Information

Product Name	n-Cbz-(R)-2-Amino-1-Butanol
CAS No.	73395-16-1
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	(R)-2-[(Benzyloxy)carbonylamino]-1-butanol; (R)-N-Carbobenzoxy-2-amino-1-butanol; (R)-N-Cbz-2-amino-1-butanol; (R)-2-(Benzyloxycarbonylamino)butan-1-ol; (R)-N-[(Benzyloxy)carbonyl]-2-aminobutan-1-ol; (R)-2-(Cbz-amino)-1-butanol; (R)-2-Amino-1-butanol N-carboxybenzyl derivative; Z-(R)-2-Abu-ol
EINECS	Contact for details

Quality Control

Our n-Cbz-(R)-2-Amino-1-Butanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically >98%), enantiomeric excess (ee), and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.