Description

Acetamide, 2-Bromo-N-(3-fluorophenyl)- is a specialized halogenated aromatic amide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique bromo-fluoro substitution pattern enables precise molecular modifications. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated aromatic core.
• Material Science: Acts as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with specific electronic or optical properties.
• Chemical Biology Probe Synthesis: Employed to build molecular probes for studying enzyme function and protein-ligand interactions within biological systems.
• Organic Synthesis Building Block: Provides a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aryl and heteroaryl groups.

Basic Information

Product Name	Acetamide, 2-Bromo-N-(3-fluorophenyl)-
CAS No.	73392-04-8
Molecular Formula	C8H7BrFNO
Molecular Weight	232.05 g/mol
Synonyms	2-Bromo-N-(3-fluorophenyl)acetamide; N-(3-Fluorophenyl)-2-bromoacetamide; 2-Bromoacet-3'-fluoroanilide; α-Bromo-3'-fluoroacetanilide; 3-Fluoro-2'-bromoacetanilide; Bromoacetyl-3-fluoroaniline; (3-Fluorophenyl)carbamoylmethyl bromide
EINECS	Contact for details

Quality Control

Our Acetamide, 2-Bromo-N-(3-fluorophenyl)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.