Description

Cefoxitin CAS NO 73356-24-8 is a second-generation, broad-spectrum cephamycin antibiotic derived from cephamycin C. This semi-synthetic compound is valued for its stability against β-lactamase enzymes, making it effective against a range of Gram-positive and Gram-negative bacteria. It is primarily utilized in the pharmaceutical industry for the formulation of injectable antibiotics, serving as a critical active pharmaceutical ingredient (API) for treating serious infections. Its reliable efficacy underpins its importance in hospital and clinical settings worldwide.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations for systemic antibacterial therapy.
• Hospital Infection Control: Treatment of severe infections including intra-abdominal, gynecological, skin and soft tissue infections, and septicemia.
• Surgical Prophylaxis: Used pre-operatively to prevent post-surgical infections, particularly in colorectal and obstetric-gynecologic surgeries.
• Research & Development: Serves as a reference standard and intermediate in microbiological research and the development of new antibiotic agents.
• Veterinary Medicine: Application in treating bacterial infections in animals under veterinary supervision.

Basic Information

Product Name	Cefoxitin
CAS No.	73356-24-8
Molecular Formula	C16H17N3O7S2
Molecular Weight	427.45 g/mol
Synonyms	Cefoxitin Sodium; 3-[[(Aminocarbonyl)oxy]methyl]-7α-methoxy-7-[2-(2-thienyl)acetamido]-3-cephem-4-carboxylic Acid; (6R,7S)-3-[(Carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Mefoxin; Cefoxitin Acid; Cefoxitin Base; Cefoxitinum
EINECS	Contact for details

Quality Control

Our Cefoxitin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and support regulatory compliance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider conditions that minimize exposure to humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
pH (1% solution)	4.0 - 6.5
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Optical Rotation	+212° to +222°
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.