Description

5-(2-Fluoro-Phenylamino)-[1,3,4]Thiadiazole-2-Thiol is a specialized heterocyclic organic compound featuring a thiadiazole core substituted with a thiol group and a 2-fluoroaniline moiety. This molecular structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in creating new molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiadiazole-thiol structure.
• Material Science: Serves as a precursor for ligands in catalytic systems or as a monomer for specialized polymers with unique electronic or thermal properties.
• Chemical Synthesis: Acts as a versatile reagent for constructing complex heterocyclic frameworks in academic and industrial research settings.
• Bioconjugation & Probe Development: The reactive thiol group can be utilized for labeling proteins or other biomolecules in diagnostic or biochemical research.

Basic Information

Product Name	5-(2-Fluoro-Phenylamino)-[1,3,4]Thiadiazole-2-Thiol
CAS No.	73310-96-0
Molecular Formula	C8H6FN3S2
Molecular Weight	227.28 g/mol
Synonyms	5-[(2-Fluorophenyl)amino]-1,3,4-thiadiazole-2-thiol; 2-Fluoro-N-(5-mercapto-1,3,4-thiadiazol-2-yl)aniline; 5-(2-Fluoroanilino)-1,3,4-thiadiazole-2-thiol; 2-Fluoro-5-(1,3,4-thiadiazol-2-ylthio)aniline; 73310-96-0; 5-(2-Fluorophenylamino)-1,3,4-thiadiazole-2-thiol; 2-Mercapto-5-(2-fluorophenylamino)-1,3,4-thiadiazole
EINECS	Contact for details

Quality Control

Our production of 5-(2-Fluoro-Phenylamino)-[1,3,4]Thiadiazole-2-Thiol adheres to stringent internal quality standards to ensure batch-to-batch consistency and purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical intermediate applications, and specifications can be aligned with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.