Description

2-Bromo-6-Hydroxybenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a phenolic hydroxyl group ortho to a nitrile, makes it a critical precursor for constructing complex heterocycles and functionalized aromatic systems. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used as a building block in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and enzyme activity.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Bromo-6-Hydroxybenzonitrile
CAS No.	73289-85-7
Molecular Formula	C7H4BrNO
Molecular Weight	198.02 g/mol
Synonyms	6-Hydroxy-2-bromobenzonitrile; 2-Bromo-6-cyanophenol; 2-Bromo-6-hydroxybenzenecarbonitrile; Benzonitrile, 2-bromo-6-hydroxy-; 2-Brom-6-hydroxybenzonitril (German); 2-ブロモ-6-ヒドロキシベンゾニトリル (Japanese); (2-Bromo-6-hydroxyphenyl)methanenitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Hydroxybenzonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, guaranteeing traceability and consistent performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.