Description

1-Azabicyclo[4.4.0]decane-3-carbonitrile is a specialized bicyclic nitrile compound with a unique bridged-ring structure. This heterocyclic building block is valued for its rigid molecular framework, which is crucial for imparting specific conformational properties in advanced chemical synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and as a key intermediate in the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its bicyclic structure can contribute to unique biological activity.
• Ligand and Catalyst Development: Acts as a scaffold for creating novel ligands in asymmetric catalysis and organometallic chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specialized thermal or mechanical properties.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Azabicyclo[4.4.0]decane-3-carbonitrile
CAS No.	73259-83-3
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	3-Cyano-1-azabicyclo[4.4.0]decane; 1-Azabicyclo[4.4.0]decane-3-carbonitrile; 3-Quinuclidinecarbonitrile; Quinuclidine-3-carbonitrile; 1-Azabicyclo[2.2.2]octane-3-carbonitrile (common misnomer); Bicyclo[4.4.0]decane-3-carbonitrile, 1-aza-; 3-Cyanoquinuclidine
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[4.4.0]decane-3-carbonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects requiring material for GMP or non-GMP applications and can tailor purity grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.