Description

D-Alanine, n-Chloro- (9Ci) is a chiral, halogenated derivative of the amino acid alanine, distinguished by its D-configuration and a chloro substituent on the nitrogen atom. This specific stereochemistry and functionalization make it a valuable non-natural building block for advanced organic synthesis and pharmaceutical research. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for peptidomimetics and enzyme inhibitors.
• Agrochemical Research: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators where the D-configuration can influence biological activity and environmental stability.
• Peptide Chemistry: Acts as a modified amino acid residue for constructing custom peptides with altered backbone properties, stability, or receptor binding profiles.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme mechanisms, protein-protein interactions, and cellular pathways.
• Ligand Synthesis for Catalysis: Useful for preparing chiral ligands used in asymmetric catalysis, enhancing the enantioselectivity of synthetic transformations.
• Academic & Institutional Research: A critical reagent for universities and research institutes conducting studies in synthetic methodology, medicinal chemistry, and stereochemistry.

Basic Information

Item	Details
Product Name	D-Alanine, n-Chloro- (9Ci)
CAS No.	73170-45-3
Molecular Formula	C₃H₆ClNO₂
Molecular Weight	123.54 g/mol
Synonyms	(R)-2-Amino-N-chloropropanamide; N-Chloro-D-alanine; D-2-Aminopropionchloramide; (R)-N-Chloroalanine; Chloro-D-alanine; D-Alanine, N-chloro-; N-Chloro-(R)-alanine; Alanine, N-chloro-, D-
EINECS	Contact for details

Quality Control

Our D-Alanine, n-Chloro- (9Ci) is produced under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, potency, and consistency. A Certificate of Analysis (COA) detailing specific results for assay, enantiomeric excess, and related substances is provided with every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.