Description

Ivermectin B1 Aglycon is a key chemical intermediate and reference standard derived from the avermectin family of compounds. This high-purity substance is critical for research, development, and quality control processes in the pharmaceutical and agrochemical sectors. It is primarily utilized by manufacturers and R&D laboratories involved in the synthesis of novel antiparasitic agents and the analytical verification of related products.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced antiparasitic drugs and novel derivatives.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of ivermectin and related compounds via HPLC, LC-MS, or other chromatographic techniques.
• Veterinary Medicine Research: Serves as a precursor or active ingredient in the development of new formulations for animal health applications.
• Agrochemical Research: Investigated for potential use in the development of new, high-efficacy crop protection agents.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand the breakdown and activity of ivermectin.

Basic Information

Product Name	Ivermectin B1 Aglycon
CAS No.	73162-95-5
Molecular Formula	C₄₈H₇₄O₁₄
Molecular Weight	875.1 g/mol
Synonyms	22,23-Dihydroavermectin B1a aglycone; 5-O-Demethyl-22,23-dihydroavermectin A1a aglycone; Ivermectin B1a Aglycone; Ivermectin Aglycone; Avermectin B1a Aglycone, Dihydro-; 22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)avermectin A1a
EINECS	Contact for details

Quality Control

Our Ivermectin B1 Aglycon is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from advanced techniques like HPLC and NMR. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.