Description

cis-2-Hydroxy-1-Cyclohexanecarboxamide is a chiral, functionalized cyclohexane derivative with a hydroxyl group and a carboxamide moiety in a specific stereochemical configuration. This compound serves as a valuable intermediate and building block in sophisticated organic synthesis, particularly for the development of pharmaceuticals and fine chemicals. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers seeking to create novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in stereoselective synthesis to introduce the cis-2-hydroxycyclohexyl fragment into complex molecular architectures.
• Agrochemical Research: Serves as a building block for the synthesis of novel herbicides, fungicides, or plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of novel chiral ligands for metal-catalyzed reactions or organocatalysts.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic Research: A compound of interest in organic chemistry studies focusing on cyclization reactions, amide chemistry, and stereochemistry.

Basic Information

Item	Details
Product Name	cis-2-Hydroxy-1-Cyclohexanecarboxamide
CAS No.	73045-98-4
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1R,2S)-2-Hydroxycyclohexanecarboxamide; (1S,2R)-2-Hydroxycyclohexanecarboxamide; cis-2-Hydroxycyclohexanecarboxamide; 2-Hydroxycyclohexanecarboxamide; rel-(1R,2S)-2-Hydroxycyclohexanecarboxamide; Cyclohexanecarboxamide, 2-hydroxy-, cis-
EINECS	Contact for details

Quality Control

Our cis-2-Hydroxy-1-Cyclohexanecarboxamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess (where applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.