Description

n-Carbobenzoxy-N'-(tert-Butoxycarbonyl)Diaminomethane is a specialized bifunctional protecting group reagent used in advanced organic synthesis. This compound is critical for the selective protection of amine functionalities, particularly in the multi-step synthesis of complex molecules like peptides and pharmaceuticals. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Peptide Synthesis: As a key reagent for the orthogonal protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediate: In the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) requiring selective amine masking.
• Organic Synthesis Building Block: For constructing complex molecular architectures in medicinal chemistry and process development.
• Bioconjugation Chemistry: Used in the modification of biomolecules where selective amine protection is required before further functionalization.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and novel chemical entities.
• Fine Chemical Production: Employed in the scaled-up manufacture of specialty chemicals and advanced intermediates.

Basic Information

Product Name	n-Carbobenzoxy-N'-(tert-Butoxycarbonyl)Diaminomethane
CAS No.	73017-99-9
Molecular Formula	C15H20N2O4
Molecular Weight	292.33 g/mol
Synonyms	1,1'-[Methylenebis(oxy)]bis[2,2-dimethyl-1-oxopropane-1,3-diyl] dicarbamate; N-[(Benzyloxy)carbonyl]-N'-(tert-butoxycarbonyl)diaminomethane; Cbz-Boc-Diaminomethane; Z-Boc-Diaminomethane; (N-Carbobenzoxy-N'-tert-butoxycarbonyl)diaminomethane; Boc-Cbz-Diaminomethane; 1,1'-Carbonyldioxybis(2,2-dimethylpropyl) dicarbamate (related); Diaminomethane, N-carbobenzoxy-N'-tert-butoxycarbonyl-
EINECS	Contact for details

Quality Control

Our n-Carbobenzoxy-N'-(tert-Butoxycarbonyl)Diaminomethane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.