Description

Dynorphin A (1-13) is a potent endogenous opioid peptide, specifically the N-terminal 1-13 fragment of the full-length Dynorphin A neuropeptide. This compound is a critical research tool for studying the kappa opioid receptor (KOR) system, which is involved in pain modulation, stress responses, and reward pathways. It is essential for neuroscientists, pharmacologists, and biochemical researchers in academic, pharmaceutical, and biotechnology sectors.

Application

• Neuroscience Research: A key ligand for investigating the physiological and pathological roles of the kappa opioid receptor (KOR) in the central nervous system.
• Pharmacology Studies: Used in receptor binding assays, signal transduction experiments, and functional studies to screen and characterize novel analgesic compounds.
• Pain Research: Fundamental for understanding endogenous pain control mechanisms and developing non-addictive pain therapeutics.
• Behavioral Studies: Applied in animal models to study stress, depression, addiction, and reward-related behaviors mediated by the dynorphin/KOR system.
• Biochemical Standard: Serves as a reference standard in mass spectrometry, chromatography (HPLC), and peptide quantification assays.
• Cell Biology: Used in cell-based assays to study receptor internalization, G-protein coupling, and downstream cellular effects.

Basic Information

Item	Details
Product Name	Dynorphin A (1-13)
CAS No.	72957-38-1
Molecular Formula	C78H125N23O21
Molecular Weight	1680.0 g/mol
Synonyms	Dynorphin A (1-13) amide; Dynorphin A 1-13; Dynorphin A Fragment 1-13; [Des-Tyr14]-Dynorphin A (1-13); Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH; Dynorphin A (1-13) peptide
EINECS	Contact for details

Quality Control

Our Dynorphin A (1-13) is manufactured under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing purity, peptide content, and analytical results. Our quality commitment ensures batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.