Description

[3,4-Dihydroxy-5-(Methylsulfanylmethyl)Oxolan-2-Yl]Oxyphosphonic Acid is a high-purity organophosphorus compound with a unique chemical structure that combines a modified sugar moiety with a phosphonic acid group. This compound matters for its role as a key intermediate in the synthesis of novel nucleoside analogues and other biologically active molecules, offering researchers and manufacturers a precise building block for pharmaceutical development. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical sectors focused on antiviral, anticancer, and enzyme inhibitor research.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of modified nucleosides and nucleotide analogues with potential antiviral or anticancer activity.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, phosphatases, and other phosphotransferases.
• Prodrug Development: Serves as a precursor in the design of prodrugs aimed at improving drug delivery and bioavailability.
• Agrochemical Synthesis: Intermediate in the research and development of new plant growth regulators or herbicides with novel modes of action.
• Ligand for Metal Chelation: The phosphonic acid group allows it to act as a chelating agent in catalytic systems or metal sequestration applications.
• Fine Chemical Synthesis: Valuable chiral synthon for constructing complex molecules in asymmetric synthesis and medicinal chemistry projects.

Basic Information

Product Name	[3,4-Dihydroxy-5-(Methylsulfanylmethyl)Oxolan-2-Yl]Oxyphosphonic Acid
CAS No.	72843-83-5
Molecular Formula	C6H13O7PS
Molecular Weight	260.20 g/mol
Synonyms	5'-Deoxy-5'-(methylthio)adenosine 3'-monophosphate analogue; (2R,3S,4R,5R)-5-[(Methylsulfanyl)methyl]-3,4-dihydroxytetrahydrofuran-2-yl phosphonic acid; 5'-S-Methyl-5'-thioadenosine 3'-monophosphonate; 5'-Deoxy-5'-(methylthio)adenosine 3'-phosphonic acid; MT-AMP analogue; 3'-Phosphonomethyl-5'-thio-5'-deoxyadenosine precursor; 5'-(Methylthio)-5'-deoxyadenosine-3'-phosphonic acid
EINECS	Contact for details

Quality Control

Our [3,4-Dihydroxy-5-(Methylsulfanylmethyl)Oxolan-2-Yl]Oxyphosphonic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and cGMP-grade standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.