Description

Pergolide Sulfone is a high-purity chemical intermediate of significant importance in advanced pharmaceutical synthesis. Its primary value lies in its role as a key building block for the development of specialized active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing organizations in the pharmaceutical and life sciences sectors, particularly those focused on neurological and endocrine research applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the research and development of compounds targeting dopamine receptor pathways.
• Endocrine Research: Serves as a key material in studies related to hormonal regulation and related therapeutic areas.
• Process Development: Employed in scaling up and optimizing synthetic routes for commercial pharmaceutical production.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical laboratories.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	Pergolide Sulfone
CAS No.	72822-03-8
Molecular Formula	C19H26N2O3S
Molecular Weight	362.49 g/mol
Synonyms	8β-[(Methylthio)methyl]-6-propylergoline-1-carboxamide S,S-dioxide; Pergolide S,S-Dioxide; (8β)-6-Propyl-8-[(methylsulfonyl)methyl]ergoline-1-carboxamide; LY127809; Pergolide Sulfoxide (common misnomer); Pergolide Metabolite II; Pergolide Sulfone Derivative
EINECS	Contact for details

Quality Control

Our Pergolide Sulfone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles where applicable to support our clients' pharmaceutical development and manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.