Description

1-(3-Fluoro-4-Nitrophenyl)Ethanone is a high-purity fluorinated aromatic ketone intermediate, distinguished by its nitro and fluoro substituents which impart significant reactivity for further chemical synthesis. This compound is critical for research and development chemists requiring precise building blocks for complex molecule construction. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to the development of advanced electronic and optical materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and reduction reactions to create complex fluorinated aromatic structures.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized fluorinated dyes and pigments with unique color fastness and properties.

Basic Information

Product Name	1-(3-Fluoro-4-Nitrophenyl)Ethanone
CAS No.	72802-25-6
Molecular Formula	C8H6FNO3
Molecular Weight	183.14 g/mol
Synonyms	3'-Fluoro-4'-nitroacetophenone; 1-Acetyl-3-fluoro-4-nitrobenzene; 3-Fluoro-4-nitroacetophenone; 4-Nitro-3-fluoroacetophenone; 3-Fluoro-4-nitroacetylbenzene; Ethanone, 1-(3-fluoro-4-nitrophenyl)-; 3-Fluoro-4'-nitroacetophenone
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-4-Nitrophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers. Recommended storage temperature is between 15°C and 25°C. The container must be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	88°C - 92°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.