Description

3-(2-Cyanoethyl)Thymidine is a modified nucleoside derivative, a key synthetic intermediate in the production of oligonucleotides and other advanced biomolecules. This compound is essential for researchers and manufacturers developing novel therapeutic agents, diagnostic probes, and tools for genetic research. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors where high-purity building blocks are required for nucleic acid synthesis.

Application

• Oligonucleotide Synthesis: A crucial phosphoramidite precursor for the solid-phase synthesis of DNA and RNA strands.
• Antiviral & Anticancer Drug Development: Serves as a modified building block in the research and production of nucleoside analog prodrugs.
• Probe & Primer Manufacturing: Used to create labeled or modified probes for PCR, sequencing, and diagnostic assays.
• Bioconjugation & Linker Chemistry: The cyanoethyl group provides a handle for further chemical modifications and attachment to other molecules or surfaces.
• Academic & Industrial Research: A valuable reagent for studying nucleic acid chemistry, enzyme mechanisms, and developing new biotechnological methods.

Basic Information

Product Name	3-(2-Cyanoethyl)Thymidine
CAS No.	72718-33-3
Molecular Formula	C13H17N3O5
Molecular Weight	295.29 g/mol
Synonyms	1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione; 3-O-(2-Cyanoethyl)thymidine; Thymidine, 3-(2-cyanoethyl) ether; 5-Methyl-2'-deoxyuridine 3'-(2-cyanoethyl) ether; NSC 401071; 3-Cyanoethylthymidine
EINECS	Contact for details

Quality Control

Our 3-(2-Cyanoethyl)Thymidine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP-grade synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material for qualification under your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.