Description

Boc-L-Tyrosine Ethyl Ester is a protected derivative of the amino acid L-Tyrosine, widely used as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers who require precise control over amino acid side-chain reactivity during the construction of complex peptides and peptidomimetics. It is a key intermediate for the pharmaceutical, biotechnology, and life science research industries, enabling the development of therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental N-α-Boc protected amino acid derivative for the sequential assembly of peptide chains on resin supports.
• Solution-Phase Peptide Synthesis: Used in classical solution-phase methodologies for constructing peptide fragments and small peptides.
• Pharmaceutical Intermediate: Serves as a critical raw material in the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Employed in the study of protein structure-function relationships, enzyme substrates, and receptor ligands.
• Production of Modified Peptides: The protected phenolic -OH group allows for selective modification or deprotection, facilitating the synthesis of phosphorylated, glycosylated, or otherwise functionalized tyrosine-containing peptides.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive compounds.

Basic Information

Product Name	Boc-L-Tyrosine Ethyl Ester
CAS No.	72594-77-5
Molecular Formula	C₁₆H₂₃NO₅
Molecular Weight	309.36 g/mol
Synonyms	Boc-Tyr-OEt; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(4-hydroxyphenyl)propanoic acid ethyl ester; N-α-tert-Butyloxycarbonyl-L-tyrosine ethyl ester; N-Boc-L-tyrosine ethyl ester; Boc-L-Tyrosine O-ethyl ester; Ethyl N-(tert-butoxycarbonyl)-L-tyrosinate; tert-Butyloxycarbonyl-L-tyrosine ethyl ester; BOC-TYR-OET
EINECS	Contact for details

Quality Control

Our Boc-L-Tyrosine Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.