Description

6β-Hydroxy 21-(Acetyloxy) Triamcinolone Acetonide is a key synthetic corticosteroid derivative, primarily valued as a critical intermediate in the pharmaceutical synthesis of more complex and potent steroid-based active pharmaceutical ingredients (APIs). Its precise chemical structure allows for targeted modifications, making it essential for research and development in advanced therapeutic areas. This compound is of significant interest to pharmaceutical manufacturers and R&D laboratories focused on developing anti-inflammatory, immunosuppressive, and dermatological treatments.

Application

• Pharmaceutical Intermediate: Primary use as a high-purity building block in the multi-step synthesis of advanced corticosteroid APIs.
• Anti-inflammatory Drug Research: Serves as a precursor in the development of novel topical and systemic anti-inflammatory medications.
• Dermatological Formulations: Used in R&D for creating potent agents to treat conditions like psoriasis, eczema, and dermatitis.
• Immunosuppressant Synthesis: A key starting material for researchers developing new immunosuppressive therapies.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Process Chemistry & Scale-up: Utilized in process optimization and pilot-scale production for new steroid-based drugs.

Basic Information

Product Name	6β-Hydroxy 21-(Acetyloxy) Triamcinolone Acetonide
CAS No.	72559-83-2
Molecular Formula	C26H33FO8
Molecular Weight	492.54 g/mol
Synonyms	21-Acetoxy-6β-hydroxy triamcinolone acetonide; 6β-Hydroxytriamcinolone acetonide 21-acetate; 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 6β-hydroxy, 21-acetate; Triamcinolone acetonide 6β-hydroxy-21-acetate; 6β-Hydroxy-21-O-acetyltriamcinolone acetonide; 21-Acetyloxy-6β-hydroxytriamcinolone acetonide
EINECS	Contact for details

Quality Control

Our 6β-Hydroxy 21-(Acetyloxy) Triamcinolone Acetonide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of API intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.