Description

Ceftazidime CAS NO 72558-82-8 is a third-generation, broad-spectrum cephalosporin antibiotic belonging to the β-lactam class. It is valued for its potent activity against a wide range of Gram-negative bacteria, including *Pseudomonas aeruginosa*, and its stability against many β-lactamases. This makes it a critical active pharmaceutical ingredient (API) for the formulation of injectable antibiotics used in hospital and clinical settings to treat serious infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations (powder for solution).
• Hospital-Acquired Infections: Treatment of severe infections including pneumonia, bacteremia, and septicemia.
• Immunocompromised Patients: Critical therapy for infections in patients with neutropenia, cystic fibrosis, or burns.
• Intra-Abdominal & Urinary Tract Infections: Used in complicated intra-abdominal infections and complicated urinary tract infections (UTIs).
• Meningitis: Treatment of bacterial meningitis, particularly when caused by susceptible Gram-negative organisms.
• Veterinary Medicine: Used in certain high-value veterinary applications for treating bacterial infections.
• Research & Development: Serves as a reference standard and key intermediate in antimicrobial research and new drug development.

Basic Information

Product Name	Ceftazidime
CAS No.	72558-82-8
Molecular Formula	C22H22N6O7S2
Molecular Weight	546.58 g/mol
Synonyms	Ceftazidime Pentahydrate; Ceptaz; Fortaz; Tazicef; Tazidime; GR-20263; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Glazidim
EINECS	276-683-6

Quality Control

Our Ceftazidime is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP, EP, and JP. Each batch undergoes rigorous analytical testing including HPLC for assay and related substances, identification by IR and HPLC, and tests for residual solvents, water content, and specific optical rotation. A comprehensive Certificate of Analysis (COA) documenting all specifications is provided with every shipment to ensure traceability and quality assurance for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation. For long-term storage, consider desiccants or inert atmosphere packing.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC, anhydrous basis)	96.0% - 102.0%
pH (10% suspension)	3.0 - 4.0
Specific Optical Rotation	-15° to -25°
Water (Karl Fischer)	10.0% - 13.0% (for pentahydrate)
Related Substances (HPLC)	Individual impurity: NMT 1.0% Total impurities: NMT 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.