Description

(S)-5-(Bromomethyl)-2-Pyrrolidinone CAS NO 72479-05-1 is a high-value chiral building block and pharmaceutical intermediate. This compound matters for its role as a key synthon in the stereoselective synthesis of complex molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of various therapeutic agents, including nootropic drugs, enzyme inhibitors, and antiviral compounds.
• Asymmetric Synthesis: Used as a versatile building block for constructing complex, enantiomerically pure molecules due to its reactive bromomethyl group and chiral center.
• Agrochemical Research: Serves as an intermediate in the development of novel, chiral pesticides and herbicides.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and other tools for studying enzyme function and protein interactions.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique optical or mechanical properties.
• Academic & Contract Research: Utilized in organic chemistry research for methodology development and the synthesis of novel chemical libraries.

Basic Information

Product Name	(S)-5-(Bromomethyl)-2-Pyrrolidinone
CAS No.	72479-05-1
Molecular Formula	C5H8BrNO
Molecular Weight	178.03 g/mol
Synonyms	(S)-5-(Bromomethyl)pyrrolidin-2-one; (S)-α-Bromo-γ-butyrolactam; (S)-N-Boc-4-(bromomethyl)-2-pyrrolidinone (protected form); (S)-4-(Bromomethyl)-2-oxopyrrolidine; (S)-2-Pyrrolidinone, 5-(bromomethyl)-; (S)-Bromomethyl GBL; (S)-Bromomethyl butyrolactam; (S)-5-Bromomethyl-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our (S)-5-(Bromomethyl)-2-Pyrrolidinone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.