Description

1-Ethynyl-Cyclohexanecarboxylic Acid is a specialized alkyne-substituted carboxylic acid building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a reactive ethynyl group and a carboxylic acid moiety, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as medicinal chemistry, polymer modification, and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for creating alkyne-functionalized scaffolds used in drug discovery and development.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, where its functional groups allow for the introduction of specific biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for synthesizing specialty polymers, resins, and advanced materials with tailored properties.
• Click Chemistry Reagent: The terminal alkyne group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of bioconjugation and material labeling.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs), leveraging the coordinating ability of the carboxylic acid.
• Academic & Industrial R&D: A valuable reagent for methodological studies and the exploration of new synthetic pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	1-Ethynyl-Cyclohexanecarboxylic Acid
CAS No.	72335-58-1
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	1-Ethynylcyclohexanecarboxylic Acid; Cyclohexanecarboxylic Acid, 1-Ethynyl-; 1-Ethynyl-1-cyclohexanecarboxylic Acid; 1-Carboxy-1-ethynylcyclohexane; Ethynylcyclohexanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 1-Ethynyl-Cyclohexanecarboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We are committed to supplying material that meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.