Description

Foscarnet Impurity A is a critical reference standard used in the analytical profiling and quality control of the antiviral drug Foscarnet. This compound is essential for pharmaceutical manufacturers and research laboratories to ensure product purity, safety, and regulatory compliance. It is primarily utilized in the development, validation, and routine testing of Foscarnet sodium active pharmaceutical ingredients (APIs) and finished drug products.

Application

• Pharmaceutical Reference Standard: Serves as a certified impurity standard for method development and validation in HPLC and LC-MS analysis.
• Quality Control & Assurance: Used for the identification, qualification, and quantification of Foscarnet Impurity A in API and drug product batches to meet ICH guidelines.
• Regulatory Compliance: Supports regulatory filings (e.g., FDA, EMA) by providing essential impurity data for drug master files (DMFs) and new drug applications (NDAs).
• Stability Studies: Employed to monitor impurity profiles in stability testing of Foscarnet formulations under various storage conditions.
• Research & Development: Aids in synthetic route optimization and impurity fate and tolerance studies during process development.

Basic Information

Product Name	Foscarnet Impurity A
CAS No.	72305-00-1
Molecular Formula	C5H4N3O4Na
Molecular Weight	193.10 g/mol
Synonyms	Sodium 5-cyano-2,4-dihydroxypyrimidine-6-olate; 5-Cyano-2,4-dihydroxypyrimidine-6-ol sodium salt; 6-Hydroxy-5-cyanopyrimidine-2,4(1H,3H)-dione sodium salt; Trisodium phosphonoformate impurity A; Foscarnet related compound A; PFA Impurity A
EINECS	Contact for details

Quality Control

Our Foscarnet Impurity A is manufactured under strict quality management systems. Each batch is characterized and tested using advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure high purity and accurate identification. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.