Description

4-Iodobenzoylacebutolol is a high-purity, specialized organic compound identified by CAS number 72249-70-8, serving as a critical intermediate in advanced pharmaceutical synthesis. Its unique molecular structure, featuring both an iodobenzoyl group and an acebutolol moiety, makes it an essential building block for research and development of novel β-blocker derivatives and other active pharmaceutical ingredients (APIs). This compound is primarily targeted at pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and production of novel cardiovascular drugs, particularly β-adrenergic blocking agents (β-blockers).
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Process Chemistry: Employed in route scouting, optimization, and scale-up studies for API manufacturing processes.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Research: Potential tool compound for studying adrenergic receptor interactions and related biochemical pathways.

Basic Information

Product Name	4-Iodobenzoylacebutolol
CAS No.	72249-70-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-Iodobenzoyl Acebutolol; Acebutolol 4-Iodobenzoate; 1-(2-Acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-3-(4-iodobenzoyl)urea (related structure); 72249-70-8; 4-Iodobenzoylacebutolol [USAN]; USAN 72249-70-8
EINECS	Contact for details

Quality Control

Our 4-Iodobenzoylacebutolol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.