Description

Coagulation Factor Viiia CAS NO 72175-66-7 is a high-purity, biologically active protein complex essential for the blood coagulation cascade. This critical reagent is vital for research, diagnostic development, and therapeutic applications where precise control of hemostasis is required. It is primarily utilized by pharmaceutical manufacturers, clinical research organizations, and in vitro diagnostic (IVD) kit producers.

Application

• Therapeutic Agent Production: As a key active pharmaceutical ingredient (API) in the manufacture of treatments for hemophilia A and other coagulation factor deficiencies.
• In Vitro Diagnostic (IVD) Reagents: A critical component in calibrators, controls, and test kits for clinical assays measuring Factor VIII activity or related coagulation parameters.
• Biomedical Research: Used in laboratory studies to investigate the mechanisms of blood coagulation, thrombosis, and hemostasis.
• Quality Control & Standardization: Serves as a reference standard for potency assays in the quality control of commercial Factor VIII products.
• Cell Culture & Tissue Engineering: Employed in specialized media formulations to study endothelial cell function and vascular biology.

Basic Information

Product Name	Coagulation Factor Viiia
CAS No.	72175-66-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Antihemophilic Factor; Factor VIII; AHF; FVIII; Blood Coagulation Factor VIII; Coagulation Factor VIIIa; Activated Factor VIII; Factor VIII Activating Component; Thromboplastinogen; Antihemophilic Globulin (AHG); Hemofil M; Koate-DVI
EINECS	Contact for details

Quality Control

Our Coagulation Factor Viiia is manufactured and tested under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, meeting the rigorous standards required for pharmaceutical and diagnostic applications. Certificates of Analysis (COA) detailing specific test results, including activity (IU/mg), purity by HPLC, and relevant impurity profiles, are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Handle under aseptic conditions as appropriate for its intended pharmaceutical or diagnostic use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/Activity)	Conforms to standard
Assay (Potency)	≥ XX IU/mg protein (Grade Dependent)
Purity (SDS-PAGE / HPLC)	≥ 95%
Specific Activity	Contact for details
pH (in solution)	6.5 - 7.5
Endotoxin	< 1.0 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.