Description

3-(4-Chloro-Phenyl)-2-Thiocyanato-Propionitrile is a specialized organic intermediate featuring a unique combination of chloro-phenyl, nitrile, and thiocyanate functional groups. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research and development chemists, process development scientists, and manufacturers in fine chemical and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial activity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its chloro-phenyl moiety for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold for heterocyclic chemistry, enabling the construction of thiazole, thiadiazole, and other sulfur/nitrogen-containing ring systems.
• Material Science Applications: Potential use in the synthesis of specialty polymers or liquid crystals due to its rigid aromatic core and polar functional groups.
• Dye & Pigment Intermediate: Can be utilized in the production of specialized dyes and colorants where the thiocyanate group acts as a chromophore or reactive site.

Basic Information

Product Name	3-(4-Chloro-Phenyl)-2-Thiocyanato-Propionitrile
CAS No.	72132-58-2
Molecular Formula	C10H7ClN2S
Molecular Weight	222.69 g/mol
Synonyms	2-Thiocyanato-3-(4-chlorophenyl)propionitrile; 3-(p-Chlorophenyl)-2-thiocyanatopropionitrile; 4-Chloro-α-(thiocyanatomethyl)benzeneacetonitrile; 2-Thiocyanato-3-(4'-chlorophenyl)propiononitrile; (4-Chlorophenyl)(thiocyanato)acetonitrile; Propionitrile, 3-(4-chlorophenyl)-2-thiocyanato-; 72132-58-2
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-Phenyl)-2-Thiocyanato-Propionitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.