Description

5-Amino-2-Bromobenzonitrile is a versatile aromatic nitrile and halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a bromo substituent on the benzonitrile core, makes it an indispensable intermediate for constructing complex molecular architectures. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fused heterocycles or aniline derivatives.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its halogen and amino groups for further functionalization.
• Material Science Research: Serves as a monomer or functional unit in the development of specialty polymers, dyes, and organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags, molecular probes, and bioconjugation reagents.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Amino-2-Bromobenzonitrile
CAS No.	72115-09-4
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	2-Bromo-5-aminobenzonitrile; 5-Amino-2-bromobenzene carbonitrile; 2-Bromo-5-cyanobenzenamine; Benzonitrile, 5-amino-2-bromo-; 5-Amino-o-bromobenzonitrile; 2-Bromo-5-aminobenzene nitrile; (2-Bromo-5-aminophenyl) cyanide
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Bromobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of our clients in regulated industries. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.