Description

(1S,2S)-(+)-1,2-Bis[(n-Diphenylphosphino)Amino]Cyclohexane is a high-value, chiral bisphosphine ligand widely used in asymmetric catalysis. Its primary value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing optically pure intermediates in fine chemical and pharmaceutical synthesis. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and effective chiral auxiliaries. CAS No. 72090-83-6.

Application

• As a chiral ligand for asymmetric hydrogenation reactions, crucial for producing enantiomerically pure pharmaceutical actives.
• Catalyst component in asymmetric C-C bond forming reactions, such as cross-coupling and hydroformylation.
• Key reagent in the synthesis of chiral natural products and complex organic molecules for research and development.
• Used in the development of homogeneous catalysts for industrial-scale fine chemical manufacturing.
• Critical for process chemistry in the pharmaceutical industry to ensure regulatory compliance for chiral purity.
• Research applications in academic and institutional laboratories exploring new catalytic methodologies.

Basic Information

Product Name	(1S,2S)-(+)-1,2-Bis[(n-Diphenylphosphino)Amino]Cyclohexane
CAS No.	72090-83-6
Molecular Formula	C30H32N2P2
Molecular Weight	482.54 g/mol
Synonyms	(1S,2S)-(+)-1,2-Bis(diphenylphosphinoamino)cyclohexane; (1S,2S)-Cyclohexane-1,2-diylbis[(diphenylphosphanyl)amine]; (S,S)-DACH-Phenyl Trost Ligand; (S,S)-DACH-Phenyl; (1S,2S)-1,2-Diaminocyclohexane-N,N'-bis(diphenylphosphine); (+)-1,2-Bis[(diphenylphosphino)amino]cyclohexane; (S,S)-1,2-Bis[(diphenylphosphino)amino]cyclohexane; Trost Ligand DACH-Phenyl
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-1,2-Bis[(n-Diphenylphosphino)Amino]Cyclohexane is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and key impurity profiles. We adhere to industry best practices, and specifications can be tailored to meet specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.