Description

Boc-Glu-Ome CAS NO 72086-72-7 is a protected amino acid derivative, specifically the γ-methyl ester of N-tert-butoxycarbonyl-L-glutamic acid. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Peptide Synthesis Intermediate: A key protected monomer for the Fmoc/t-Bu and Boc/Bzl strategies in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Research: Used in the R&D and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Acts as a precursor for introducing glutamic acid residues into proteins or other biomolecules for labeling or functionalization.
• Biochemical Reagent: Employed in the study of enzyme-substrate interactions and the synthesis of enzyme inhibitors or substrates.
• Combinatorial Chemistry: A valuable building block for creating diverse chemical libraries for high-throughput screening in drug discovery.
• Material Science: Used in the synthesis of peptide-polymer conjugates and bio-inspired materials.

Basic Information

Product Name	Boc-Glu-Ome
CAS No.	72086-72-7
Molecular Formula	C11H19NO6
Molecular Weight	261.27 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-glutamic acid γ-methyl ester; Boc-L-glutamic acid 5-methyl ester; (S)-2-((tert-Butoxycarbonyl)amino)pentanedioic acid 5-methyl ester; Boc-Glu(OMe)-OH; Boc-Glu-OMe; N-Boc-L-glutamic acid γ-methyl ester; Nα-Boc-L-glutamic acid 5-methyl ester; N-tert-Butoxycarbonyl-L-glutamic acid γ-methyl ester
EINECS	Contact for details

Quality Control

Our Boc-Glu-Ome is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	-15.0° to -18.0° (c=1 in AcOH)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.