Description

Histidine Permease, Salmonella Typhimurium is a specialized membrane transport protein complex. This product is essential for research into bacterial amino acid uptake mechanisms and membrane protein biochemistry. It is primarily utilized by academic, pharmaceutical, and biotechnology research laboratories studying microbial physiology, antibiotic resistance, and protein structure-function relationships.

Application

• Biochemical Research: Fundamental studies on bacterial histidine transport and membrane protein function.
• Antimicrobial Target Investigation: Used as a model system to explore novel targets for disrupting bacterial nutrient uptake.
• Protein-Protein Interaction Studies: Analysis of interactions within the ABC transporter complex and with regulatory proteins.
• Educational & Reference Standard: Serves as a high-purity reference material in advanced microbiology and biochemistry courses.
• Drug Discovery Platforms: Incorporated into screening assays to identify potential inhibitors of bacterial permease systems.
• Structural Biology: A source protein for crystallization trials and structural determination efforts (e.g., X-ray crystallography, Cryo-EM).

Basic Information

Product Name	Histidine Permease, Salmonella Typhimurium
CAS No.	72060-35-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Histidine transport protein complex; Histidine permease complex; S. Typhimurium histidine ABC transporter; Histidine-binding protein J; HisJ protein; Histidine transporter; ABC-type histidine importer; High-affinity histidine permease
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with research-grade standards. Each batch is characterized for activity and purity using appropriate biochemical and biophysical methods. Certificates of Analysis (COA) detailing specific parameters are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (SDS-PAGE)	Corresponds to expected subunit pattern
Purity (HPLC)	≥ 90%
Protein Concentration	As per COA
Biological Activity	Assessed by ligand-binding or transport assay
Endotoxin Level	< 1.0 EU/µg (if applicable)
Solubility	In specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.