Description

Desethyl-n-Acetylprocainamide is a key pharmaceutical intermediate and reference standard, primarily known for its role in the study of procainamide metabolism. This compound is of significant importance for research and development in the fields of pharmacology and analytical chemistry, providing a critical benchmark for metabolic pathway analysis and bioanalytical method validation. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions focused on cardiovascular drug research, pharmacokinetic studies, and impurity profiling.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification and quantification of metabolites in bioanalytical assays.
• Metabolite Research: Critical for studying the metabolic pathways and pharmacokinetics of the antiarrhythmic drug procainamide.
• Impurity Profiling: Employed in the development and validation of HPLC/LC-MS methods to identify and control related substances in active pharmaceutical ingredients (APIs).
• Pharmacological Studies: Serves as a tool compound in in-vitro and in-vivo studies to understand the activity and toxicity profiles of procainamide derivatives.
• Quality Control Laboratories: Utilized in pharmaceutical QC labs to ensure batch-to-batch consistency and compliance with regulatory specifications for purity.

Basic Information

Product Name	Desethyl-n-Acetylprocainamide
CAS No.	72040-49-4
Molecular Formula	C13H21N3O2
Molecular Weight	251.33 g/mol
Synonyms	N-Acetylprocainamide N-oxide; NAPA N-oxide; N-Acetyl-N-(2-diethylaminoethyl)-4-aminobenzamide N-oxide; Desethyl N-Acetyl Procainamide; Procainamide Metabolite; 4'-Amino-N-[2-(diethylamino)ethyl]benzamide N-oxide, N-acetyl-; 72040-49-4
EINECS	Contact for details

Quality Control

Our Desethyl-n-Acetylprocainamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.