Description

Methyl Lithiopropiolate is a highly reactive organolithium reagent used for the efficient introduction of the propiolate moiety in advanced organic synthesis. This compound is valued for its role as a key building block in the construction of complex molecules, particularly in pharmaceutical and agrochemical research and development. It is essential for chemists and manufacturers engaged in fine chemical synthesis, material science, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating specialized polymers and advanced organic materials.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new carbon-carbon bond forming reactions.

Basic Information

Product Name	Methyl Lithiopropiolate
CAS No.	72036-29-4
Molecular Formula	C4H3LiO2
Molecular Weight	89.99 g/mol
Synonyms	Lithium Methyl Propiolate; Methyl Propiolate Lithium Salt; Methyl 2-Propynoate, Lithium Salt; Propiolic Acid, Methyl Ester, Lithium Salt; Lithium Methyl 2-Propynoate; Methyl Lithio-2-propynoate; 2-Propynoic Acid, Methyl Ester, Lithium Salt
EINECS	Contact for details

Quality Control

Our Methyl Lithiopropiolate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and suitability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all relevant parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C. Handle and open containers only in a controlled, moisture-free environment.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Lithium Content	Contact for details
Solubility Test	Soluble in specified aprotic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.