Description

3'-Deoxyadenosine 5'-Triphosphate Sodium Salt is a chemically modified nucleotide analog where the 3'-hydroxyl group of the ribose sugar is replaced by a hydrogen atom. This structural modification makes it a valuable tool for terminating DNA synthesis in sequencing applications and for studying enzyme mechanisms, particularly those of DNA polymerases and reverse transcriptases. It is essential for researchers and manufacturers in molecular biology, biochemistry, and pharmaceutical development who require high-purity, well-characterized nucleotide derivatives for critical research and diagnostic kit production.

Application

• Molecular Biology Research: Used as a chain-terminating substrate in DNA sequencing techniques and enzymatic studies.
• Enzyme Kinetics & Mechanism Studies: Serves as a critical probe to investigate the activity and specificity of DNA-dependent polymerases and other nucleotide-processing enzymes.
• Biochemical Assay Development: Incorporated into diagnostic and research kits that require controlled termination of nucleic acid synthesis.
• Antiviral Research: Studied for its potential as an analog in the development of nucleoside reverse transcriptase inhibitors.
• Pharmaceutical Intermediates: Acts as a key synthetic intermediate or reference standard in the development of novel therapeutic agents.

Basic Information

Product Name	3'-Deoxyadenosine 5'-Triphosphate Sodium Salt
CAS No.	71997-32-5
Molecular Formula	C10H13N5O12P3·xNa
Molecular Weight	Approx. 551.1 (Free acid) + xNa
Synonyms	3'-Deoxy-ATP Sodium Salt; Cordycepin-5'-triphosphate Sodium Salt; 3'-dATP Na Salt; 3'-Deoxyadenosine triphosphate trisodium salt; 3'-Deoxy-5'-ATP Na; 9-(3-Deoxy-β-D-ribofuranosyl)adenine 5'-triphosphate sodium salt
EINECS	Contact for details

Quality Control

Our 3'-Deoxyadenosine 5'-Triphosphate Sodium Salt is manufactured under stringent controls to ensure high chemical purity and batch-to-batch consistency suitable for sensitive research applications. Quality is verified through a comprehensive battery of analytical tests including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (Solution)	6.0 - 8.0
Biological Activity	Tested in enzymatic assay (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.