Description

19-Hydroxyandrostendione-19-D2 is a deuterated derivative of the endogenous steroid hormone 19-hydroxyandrostenedione, specifically labeled with two deuterium atoms at the 19-position. This compound is of significant value as a high-purity internal standard and reference material for mass spectrometry-based analytical methods, ensuring accurate quantification in complex biological matrices. It is primarily needed by research institutions, pharmaceutical development laboratories, and contract research organizations (CROs) engaged in steroid metabolism studies, anti-doping analysis, and the development of novel endocrine therapies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, isotopically labeled internal standard for the precise quantification of 19-hydroxyandrostenedione and related steroid metabolites in biological fluids (e.g., serum, urine).
• Metabolic Pathway Research: Used as a tracer in in vitro and in vivo studies to elucidate the biosynthesis and metabolic fate of 19-hydroxylated androgens.
• Pharmaceutical Reference Standard: Employed in the quality control and method validation for the development of steroid-based pharmaceuticals and diagnostic assays.
• Doping Control Analysis: A key reference material for anti-doping laboratories to accurately identify and confirm the presence of endogenous anabolic steroid metabolites in athletes.
• Biochemical Research: Utilized in enzyme inhibition studies and receptor binding assays to investigate the role of 19-hydroxyandrostenedione in endocrine signaling.

Basic Information

Product Name	19-Hydroxyandrostendione-19-D2
CAS No.	71995-64-7
Molecular Formula	C19H26D2O3
Molecular Weight	304.45 g/mol (approx.)
Synonyms	19-Hydroxyandrost-4-ene-3,17-dione-19,19-d2; 19-Hydroxy-4-androstene-3,17-dione-19-d2; 19-Hydroxyandrostenedione-d2; 19-OH-AD-d2; 19-Hydroxy-δ4-androstenedione-19-d2; Androst-4-ene-3,17-dione, 19-hydroxy-, 19,19-d2; 19-Hydroxyandrost-4-ene-3,17-dione (19,19-d2)
EINECS	Contact for details

Quality Control

Our 19-Hydroxyandrostendione-19-D2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for chemical purity, NMR and MS for structural and isotopic confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on purity, isotopic enrichment, and all critical quality attributes. Our commitment ensures material suitable for demanding GMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.