Description

3-(5-Bromo-Thiophen-2-Yl)-3-Oxo-Propionitrile is a high-value brominated thiophene derivative and a versatile chemical building block. Its molecular structure, featuring both an electron-withdrawing nitrile group and a reactive bromine atom, makes it a critical intermediate for synthesizing complex heterocyclic compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used to construct novel fungicides, herbicides, and insecticides with enhanced efficacy and selectivity.
• Organic Electronics: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Material Science Research: Employed in the development of advanced functional materials, including dyes, pigments, and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Academic & Contract Research: A valuable reagent for university laboratories and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-(5-Bromo-Thiophen-2-Yl)-3-Oxo-Propionitrile
CAS No.	71683-02-8
Molecular Formula	C7H4BrNO2S
Molecular Weight	246.08 g/mol
Synonyms	5-Bromo-2-thienyl cyanomethyl ketone; 2-Acetyl-5-bromothiophene-3-carbonitrile; 3-Oxo-3-(5-bromothiophen-2-yl)propanenitrile; 5-Bromo-2-thienyl cyanomethyl ketone; 1-(5-Bromo-2-thienyl)-2-cyanoethanone; 2-(5-Bromo-2-thienoyl)acetonitrile; (5-Bromo-2-thienyl)(cyanomethyl)methanone; 3-(5-Bromothiophen-2-yl)-3-oxopropanenitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive; store away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.