Description

3,4-Difluorobenzoylacetonitrile is a versatile fluorinated aromatic building block and key intermediate in advanced organic synthesis. Its molecular structure, featuring both a difluorophenyl ring and a reactive acetonitrile moiety, makes it a critical precursor for the development of high-value specialty chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate fluorinated aromatic systems into novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system and anti-inflammatory agents where fluorination enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the difluorophenyl group contributes to improved efficacy and environmental profile.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Functional Material Development: Employed in the research and production of advanced materials, including liquid crystals, organic semiconductors, and polymers with tailored electronic properties.
• Chemical Research & Development: A valuable reagent for exploring novel heterocyclic chemistry, such as the synthesis of pyrazoles, isoxazoles, and other nitrogen-containing rings.

Basic Information

Product Name	3,4-Difluorobenzoylacetonitrile
CAS No.	71682-97-8
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	1-(3,4-Difluorophenyl)-3-oxobutanenitrile; 3,4-Difluorobenzoylacetonitrile; 4,4'-Difluorobenzoylacetonitrile; 3-Oxo-3-(3,4-difluorophenyl)propanenitrile; 3-(3,4-Difluorobenzoyl)propionitrile; Butanenitrile, 1-(3,4-difluorophenyl)-3-oxo-; Acetonitrile, (3,4-difluorobenzoyl)-
EINECS	Contact for details

Quality Control

Our 3,4-Difluorobenzoylacetonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.