Description

3-Amino-3-[4-(Trifluoromethyl)Phenyl]Acrylonitrile is a versatile and high-value fluorinated organic intermediate. Its molecular structure, featuring both an amino group and a nitrile adjacent to a trifluoromethyl-substituted aromatic ring, makes it a critical building block for synthesizing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors. It is particularly valuable for creating novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and aromatic characteristics.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the design of enzyme inhibitors, probes, and molecular tools for biological studies.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for fine chemical manufacturers and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-Amino-3-[4-(Trifluoromethyl)Phenyl]Acrylonitrile
CAS No.	71682-89-8
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	3-Amino-3-(4-trifluoromethylphenyl)acrylonitrile; 2-Amino-2-(4-(trifluoromethyl)phenyl)ethene-1,1-dicarbonitrile; 3-Amino-3-(4-(trifluoromethyl)phenyl)-2-propenenitrile; (2Z)-3-Amino-3-[4-(trifluoromethyl)phenyl]prop-2-enenitrile; 4-(Trifluoromethyl)benzylidenemalononitrile amine; α-Amino-α-(4-trifluoromethylbenzylidene)malononitrile; 71682-89-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Amino-3-[4-(Trifluoromethyl)Phenyl]Acrylonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.