Description

(R)-Amisulpride CAS NO 71675-90-6 is the single enantiomer of the atypical antipsychotic amisulpride, characterized by its high affinity and selectivity for dopamine D2 and D3 receptors. This compound is of significant value in pharmaceutical research and development, particularly for studying receptor-specific mechanisms and developing enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in neuroscience research, psychopharmacology, and the development of novel central nervous system (CNS) therapeutics.

Application

• Key chiral intermediate for the synthesis of enantiomerically pure (R)-Amisulpride active pharmaceutical ingredient (API).
• Reference standard for analytical method development and validation in quality control laboratories.
• Pharmacological research tool for studying the specific effects of the (R)-enantiomer on dopamine D2/D3 receptors.
• Preclinical development of novel antipsychotic medications with potentially improved efficacy or reduced side-effect profiles.
• Substrate for metabolic and pharmacokinetic studies to understand enantioselective disposition.
• Building block in medicinal chemistry programs targeting G-protein coupled receptors (GPCRs).

Basic Information

Product Name	(R)-Amisulpride
CAS No.	71675-90-6
Molecular Formula	C17H27N3O4S
Molecular Weight	369.48 g/mol
Synonyms	(R)-Amisulpride; (R)-(-)-Amisulpride; (R)-4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide; (R)-(-)-4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-ethylsulfonyl-o-anisamide; (R)-(-)-Socian; (R)-Enantiomer of Amisulpride; (R)-AminoSulpride; (R)-DA 2450
EINECS	Contact for details

Quality Control

Our (R)-Amisulpride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure identity, potency, and purity meet stringent specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.