Description

6'-Di-n-Methylfortimicin B is a chemically modified derivative of the fortimicin class of aminoglycoside antibiotics. This compound is valued as a key intermediate in pharmaceutical research and development, particularly for the synthesis of novel antimicrobial agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathway for novel aminoglycoside antibiotics.
• Antimicrobial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) against Gram-positive and Gram-negative bacteria.
• Reference Standard: Employed as an analytical standard in quality control laboratories for the identification and quantification of related compounds.
• Medicinal Chemistry: A valuable substrate for further chemical modifications aimed at improving pharmacokinetic properties or reducing ototoxicity and nephrotoxicity.

Basic Information

Product Name	6'-Di-n-Methylfortimicin B
CAS No.	71657-33-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6'-Di-N-methylfortimicin B; Fortimicin B, 6'-di-N-methyl-; 6'-Bis(N-methyl)fortimicin B; Antibiotic KA-6606 IX; (2S,4S)-2,4-Diamino-N-[(1R,2S,3S,4R,5S)-5-amino-4-[(2S,3R,4S,5S,6R)-4,5-diamino-3,6-dihydroxyoxan-2-yl]oxy-2-[(2R,3R,4R,5R,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-N-methylbutanamide
EINECS	Contact for details

Quality Control

Our 6'-Di-n-Methylfortimicin B is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.