Description

2-Bromooctanoyl-Coenzyme A is a specialized biochemical reagent, a brominated analog of octanoyl-CoA, designed for advanced research and development. This compound serves as a critical tool compound and substrate analog in the study of fatty acid metabolism, enzyme kinetics, and acyltransferase function. It is primarily utilized by researchers and scientists in pharmaceutical development, metabolic disease research, and academic biochemistry laboratories.

Application

• Enzymology Research: Used as a substrate or inhibitor in studies of acyl-CoA synthetases, acyltransferases, and other enzymes involved in lipid biosynthesis and modification.
• Metabolic Pathway Analysis: Acts as a probe to investigate β-oxidation and other fatty acid metabolic pathways, particularly to study the effects of chain-length specific bromination.
• Pharmaceutical Development: Employed in the discovery and characterization of novel therapeutics targeting metabolic disorders, such as diabetes and obesity.
• Biochemical Assay Development: Serves as a key component in developing high-throughput screening assays for enzyme activity and drug discovery platforms.
• Mechanistic Studies: Utilized to elucidate reaction mechanisms of CoA-dependent enzymes through the use of its bromine atom as a mechanistic probe or trapping agent.
• Academic Research: Fundamental research tool in university and institutional labs for studying protein-ligand interactions and cofactor chemistry.

Basic Information

Product Name	2-Bromooctanoyl-Coenzyme A
CAS No.	71605-35-1
Molecular Formula	C29H48BrN7O17P3S
Molecular Weight	988.67 g/mol
Synonyms	2-Bromooctanoyl-CoA; 2-Bromooctanoyl-Coenzyme A triammonium salt; Coenzyme A, S-(2-bromooctanoyl); S-(2-Bromooctanoyl)coenzyme A; 2-Bromo-octanoyl-CoA; Bromooctanoyl-CoA; 2-Br-Oct-CoA; Octanoyl-CoA, 2-bromo-
EINECS	Contact for details

Quality Control

Our 2-Bromooctanoyl-Coenzyme A is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated at -80°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (UV)	Spectrum corresponds to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity	Confirmed in enzymatic assay (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.