Description

Glicentin CAS NO 71567-77-6 is a proglucagon-derived peptide hormone, primarily produced in the intestinal L-cells. This compound is of significant interest in metabolic research due to its role in regulating insulin secretion and gastric acid inhibition. It is a critical reagent for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on diabetes, obesity, and gastrointestinal disorder research.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating glucose homeostasis, incretin biology, and appetite regulation.
• Pharmaceutical Development: Serves as a key intermediate or target molecule in the discovery and development of novel therapeutics for metabolic syndromes.
• Diagnostic Assays: Employed in the calibration and development of immunoassays (ELISA, RIA) for the quantitative measurement of glicentin and related peptides in biological samples.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study receptor binding, signal transduction pathways, and the physiological effects on pancreatic and gastric cells.
• Academic Research: Essential for universities and research institutes conducting fundamental research in endocrinology and molecular biology.

Basic Information

Product Name	Glicentin
CAS No.	71567-77-6
Molecular Formula	C254H381N71O73S2
Molecular Weight	Approx. 5690.4 g/mol
Synonyms	Major Proglucagon Fragment; Enteroglucagon; Glicentin (1-69); Oxyntomodulin (1-69); Pancreatic Proglucagon Fragment; GLI-1; Proglucagon 1-69; Proglucagon-Derived Peptide
EINECS	Contact for details

Quality Control

Our Glicentin is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and peptide mapping for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, endotoxin levels, and biological activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%
Endotoxin Level	< 10 EU/mg
Biological Activity	Assessed by in vitro bioassay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.