Description

3-Bromocinnamamide is a versatile brominated aromatic amide derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a cinnamamide backbone, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the cinnamic acid derivative framework.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers with enhanced thermal or optical properties.
• Organic Synthesis Building Block: Employed in Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions to introduce the bromophenyl moiety into more complex structures.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function or protein-protein interactions due to its ability to act as a Michael acceptor.
• Liquid Crystal & OLED Material Research: Investigated as a component in the synthesis of organic semiconductors and light-emitting materials.

Basic Information

Item	Detail
Product Name	3-Bromocinnamamide
CAS No.	71539-43-0
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	(E)-3-(3-Bromophenyl)acrylamide; 3-Bromocinnamic acid amide; trans-3-(3-Bromophenyl)-2-propenamide; (E)-3-(3-Bromophenyl)prop-2-enamide; 3-Bromo-trans-cinnamamide; NSC 403914; 3-Bromocinammamide; 3-Brom-Zimtsäureamid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromocinnamamide is produced and tested under a strict quality management system to ensure consistency and purity suitable for research and development applications. Standard quality control includes identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by HPLC. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment. We can support development projects requiring compliance with ICH guidelines or other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.