Description

Methoxy-D3-Flurane is a deuterated isotopologue of methoxyflurane, a halogenated ether anesthetic. This deuterated version is a critical tool in pharmaceutical research and development, particularly for metabolic and pharmacokinetic studies. It is primarily utilized by research scientists and analytical chemists in the pharmaceutical, agrochemical, and academic sectors. The incorporation of deuterium atoms provides a stable isotopic label for advanced analytical techniques.

Application

• Internal Standard for Analytical Chemistry: Used as a deuterated internal standard in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the precise quantification of methoxyflurane and related compounds.
• Metabolic Pathway Tracing: Employed in drug metabolism and pharmacokinetics (DMPK) studies to elucidate metabolic pathways, identify metabolites, and study the bioavailability of methoxyflurane.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for method development, validation, and quality control in pharmaceutical analysis.
• Isotope Dilution Mass Spectrometry (IDMS): A key component in high-precision IDMS assays due to its nearly identical chemical properties but distinct mass signature.
• Forensic and Toxicological Analysis: Used in forensic laboratories for the accurate detection and quantification of methoxyflurane in biological samples.
• Environmental Fate Studies: Applied in research to track the environmental degradation and transformation products of halogenated ether anesthetics.

Basic Information

Product Name	Methoxy-D3-Flurane
CAS No.	71444-46-7
Molecular Formula	C3H2D3Cl2F3O
Molecular Weight	168.99 g/mol (for deuterated form)
Synonyms	2,2-Dichloro-1,1-difluoro-1-methoxy-d3-ethane; Methoxyflurane-d3; Deuterated Methoxyflurane; 1-Methoxy-2,2,2-trifluoro-1,1-dichloro-d3-ethane; Penthrane-d3; NSC 110432-d3; (2,2-Dichloro-1,1-difluoroethyl) methyl-d3 ether
EINECS	Contact for details

Quality Control

Every batch of Methoxy-D3-Flurane is produced and analyzed under strict quality protocols to ensure high isotopic purity and chemical identity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment (D, atom %), chemical purity (by GC or HPLC), and identity confirmation (by NMR, IR, MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (D, atom %)	≥ 98.0% (D3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.