Description

Boc-3-(2-Pyridyl)-L-Alanine is a protected, non-proteinogenic amino acid derivative featuring a tert-butoxycarbonyl (Boc) group and a 2-pyridyl side chain. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, enabling the introduction of heterocyclic functionality with precise stereochemical control. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers developing novel bioactive molecules, including enzyme inhibitors and drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic peptides and small molecule drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a heteroaromatic side chain, influencing peptide conformation and bioactivity.
• Chemical Biology Probes: Serves as a building block for creating labeled peptides or activity-based probes to study protein function and interactions.
• Ligand Development: Employed in the synthesis of chelating ligands or metal-organic frameworks (MOFs) due to the coordinating potential of the pyridyl nitrogen.
• Agrochemical Research: Used in the design and synthesis of novel, bioactive compounds with potential pesticidal or herbicidal activity.
• Academic Research: A valuable reagent for synthetic organic chemistry studies and methodology development in asymmetric synthesis.

Basic Information

Product Name	Boc-3-(2-Pyridyl)-L-Alanine
CAS No.	71239-85-5
Molecular Formula	C14H20N2O4
Molecular Weight	280.32 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-(2-pyridinyl)-L-alanine; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(pyridin-2-yl)propanoic acid; Boc-L-3-(2-Pyridyl)alanine; Boc-3-(2-Pyridyl)-L-Ala-OH; N-Boc-3-(2-pyridyl)-L-alanine; Nα-Boc-3-(2-pyridyl)-L-alanine; BOC-3-(2-PYRIDYL)-L-ALANINE
EINECS	Contact for details

Quality Control

Our Boc-3-(2-Pyridyl)-L-Alanine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.