Description

[(4-Formyl-1-Piperazinyl)Methylene]Bisphosphonic Acid CAS NO 71230-69-8 is a specialized bisphosphonate derivative featuring a formylpiperazine moiety. This compound is of significant interest as a key synthetic intermediate and a potential pharmacophore in the development of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects targeting bone metabolism disorders and other areas where bisphosphonate chemistry is applied.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel bisphosphonate-based drug candidates.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Probe Development: Utilized in the design of enzyme inhibitors or molecular probes targeting pathways involving pyrophosphate mimics.
• Academic & Industrial R&D: Employed in basic chemical research and development of new materials with chelating properties.

Basic Information

Product Name	[(4-Formyl-1-Piperazinyl)Methylene]Bisphosphonic Acid
CAS No.	71230-69-8
Molecular Formula	C7H14N2O7P2
Molecular Weight	300.14 g/mol
Synonyms	4-Formyl-1-piperazinylmethylenediphosphonic Acid; (4-Formylpiperazin-1-yl)methylene-1,1-bisphosphonic Acid; Fosmidomycin derivative; 1-Formyl-4-(diphosphonomethyl)piperazine; 71230-69-8; (4-Formyl-1-piperazinyl)methylene-1,1-bisphosphonic acid; (4-Formylpiperazinyl)methylenebis(phosphonic acid)
EINECS	Contact for details

Quality Control

Our [(4-Formyl-1-Piperazinyl)Methylene]Bisphosphonic Acid is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.