Description

1-(4-Methylphenyl)-1-Cyclopropanecarbonitrile CAS NO 71172-78-6 is a specialized organic nitrile compound featuring a cyclopropane ring and a p-tolyl substituent, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it a valuable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced material science sectors seeking reliable and consistent quality for their synthesis workflows.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding profiles.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, or fungicides where the cyclopropane moiety can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function or cellular pathways.
• Custom Synthesis and Contract Manufacturing: A requested compound for bespoke synthesis projects in fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	1-(4-Methylphenyl)-1-Cyclopropanecarbonitrile
CAS No.	71172-78-6
Molecular Formula	C11H11N
Molecular Weight	157.21 g/mol
Synonyms	1-(p-Tolyl)cyclopropanecarbonitrile; (4-Methylphenyl)cyclopropanecarbonitrile; p-Tolylcyclopropanecarbonitrile; 1-(4-Methylphenyl)cyclopropanecarbonitrile; 1-Cyclopropanecarbonitrile, 1-(4-methylphenyl)-; α-(p-Tolyl)cyclopropanenitrile; Cyclopropanecarbonitrile, 1-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 1-(4-Methylphenyl)-1-Cyclopropanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.