Description

4-(Trifluoroacetyl)-Diphenyl Ether is a high-value fluorinated aromatic building block characterized by its diphenyl ether backbone and reactive trifluoroacetyl functional group. This compound is essential for introducing the trifluoromethyl moiety into complex molecular architectures, a key strategy for modulating the physicochemical and biological properties of target molecules. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, where the trifluoromethyl group can enhance metabolic stability and membrane permeability.
• Agrochemical Active Ingredient Development: Used to create advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Material Synthesis: Serves as a fluorinated precursor for electronic chemicals used in display and lighting technologies.
• Advanced Polymer Modification: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for constructing complex fluorinated molecules and exploring new catalytic transformations.
• Fluorinated Surfactant & Coating Additive: Acts as a building block for surface-active agents and coating components that require oil and water repellency.

Basic Information

Product Name	4-(Trifluoroacetyl)-Diphenyl Ether
CAS No.	71151-89-8
Molecular Formula	C15H9F3O2
Molecular Weight	278.23 g/mol
Synonyms	1-[4-(Phenoxy)phenyl]-2,2,2-trifluoroethanone; 4-Phenoxy-α,α,α-trifluoroacetophenone; p-Phenoxy-α,α,α-trifluoroacetophenone; 4'-Phenoxy-2,2,2-trifluoroacetophenone; 2,2,2-Trifluoro-1-(4-phenoxyphenyl)ethanone; 4-Trifluoroacetyl Diphenyl Ether; (4-Phenoxyphenyl)(trifluoro)methanone
EINECS	Contact for details

Quality Control

Our 4-(Trifluoroacetyl)-Diphenyl Ether is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.