Description

Enkephalin-Leu, Nh2(3)- CAS NO 71027-11-7 is a synthetic peptide analog of the endogenous opioid peptide [Leu]-enkephalin, featuring a specific amino-terminal modification. This compound is of significant value in neuroscience and pharmaceutical research for its role in studying opioid receptor interactions and pain modulation pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuropharmacology, analgesic drug discovery, and peptide-based therapeutic development.

Application

• Neuroscience Research: Used as a reference standard and tool compound for investigating the function and binding characteristics of delta (δ) opioid receptors.
• Analgesic Drug Discovery: Serves as a key pharmacophore model and intermediate in the design and synthesis of novel, non-addictive pain management therapeutics.
• Biochemical Assays: Employed in competitive binding assays, receptor autoradiography, and functional cell-based tests to screen and evaluate new chemical entities.
• Peptide Chemistry Studies: Utilized in academic and industrial settings to study peptide stability, metabolism, and structure-activity relationships (SAR).
• Pharmaceutical Reference Standard: Acts as a high-purity calibrant for quality control and analytical method development in peptide API manufacturing.

Basic Information

Product Name	Enkephalin-Leu, Nh2(3)- CAS NO 71027-11-7
CAS No.	71027-11-7
Molecular Formula	C28H37N5O7
Molecular Weight	555.63 g/mol
Synonyms	[Leu5]-Enkephalin, amide; Leu-Enkephalin amide; H-Tyr-Gly-Gly-Phe-Leu-NH2; YGGFL-NH2; Opioid peptide LEA; (5-L-Leucine)enkephalinamide; δ-Opioid receptor agonist peptide; L-Enkephalin, 5-L-leucine-, amide
EINECS	Contact for details

Quality Control

Our Enkephalin-Leu, Nh2(3)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all test results against stringent in-house specifications. Our quality commitment ensures material integrity for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content (AAA)	≥ 80.0%
Solubility	Soluble in DMSO, acetic acid; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.