Description

(S)-4-(Oxiran-2-ylmethoxy)Benzonitrile is a chiral epoxide derivative of high synthetic utility. This compound matters as a versatile and valuable chiral building block for the preparation of active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for asymmetric synthesis and the introduction of functionalized aromatic moieties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where stereochemistry is critical for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of chiral ligands and organocatalysts used in asymmetric transformations.
• Material Science Research: Employed in the development of chiral liquid crystals, polymers, and other functional organic materials.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including ring-opening reactions and nucleophilic additions to epoxides.

Basic Information

Product Name	(S)-4-(Oxiran-2-ylmethoxy)Benzonitrile
CAS No.	70987-80-3
Molecular Formula	C10H9NO2
Molecular Weight	175.18 g/mol
Synonyms	(S)-4-(Oxiranylmethoxy)Benzonitrile; (S)-4-(Glycidyloxy)Benzonitrile; (S)-p-Cyanophenyl Glycidyl Ether; (S)-4-(2,3-Epoxypropoxy)Benzonitrile; (S)-Epichlorohydrin-p-cyanophenyl ether derivative; (S)-2-[(4-Cyanophenoxy)methyl]oxirane; (S)-α-Epoxy-p-cyanophenylpropyl ether
EINECS	Contact for details

Quality Control

Our (S)-4-(Oxiran-2-ylmethoxy)Benzonitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with full specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.