Description

Insulin Chain B is a synthetic peptide fragment corresponding to the B-chain of the insulin molecule. This high-purity biochemical is essential for research and development in the life sciences, serving as a critical reference standard and building block. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on diabetes research, metabolic studies, and peptide synthesis.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, MS) in insulin and biosimilar development.
• Biochemical Research: Serves as a key reagent in studies investigating insulin structure, function, receptor binding, and folding mechanisms.
• Peptide Synthesis: Acts as a protected intermediate or a model compound in the solid-phase or solution-phase synthesis of insulin analogs and related peptides.
• Diagnostic Development: Employed in the production and quality control of immunoassays and test kits for measuring insulin levels.
• Metabolic Disease Studies: Utilized in preclinical research to explore the pathophysiology of diabetes and evaluate potential therapeutic agents.

Basic Information

Product Name	Insulin Chain B
CAS No.	70963-41-6
Molecular Formula	C157H232N40O47S2
Molecular Weight	3495.9 g/mol
Synonyms	Insulin B-Chain; Insulin B Chain (Oxidized); B(1-30)-Insulin human; Human Insulin B Chain; Porcine Insulin B Chain; Bovine Insulin B Chain; Insulin Chain B (Disulfide form)
EINECS	Contact for details

Quality Control

Our Insulin Chain B is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.