Description

1-(2,3-Dihydro-1,4-Benzodioxin-2-Ylcarbonyl)Piperazine Hydrochloride is a high-purity pharmaceutical intermediate and research chemical with the CAS registry number 70918-74-0. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel therapeutic agents, particularly those targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key structural component in the development and scale-up of new APIs.
• Biochemical Research: Employed in biochemical assays and as a tool compound for studying biological pathways and receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	1-(2,3-Dihydro-1,4-Benzodioxin-2-Ylcarbonyl)Piperazine Hydrochloride
CAS No.	70918-74-0
Molecular Formula	C14H17N2O3·HCl
Molecular Weight	312.76 g/mol
Synonyms	1-(1,4-Benzodioxan-2-ylcarbonyl)piperazine hydrochloride; 1,4-Benzodioxan-2-carbonyl piperazine hydrochloride; 1-(2,3-Dihydro-1,4-benzodioxin-2-carbonyl)piperazine HCl; 2-(Piperazine-1-carbonyl)-2,3-dihydro-1,4-benzodioxine hydrochloride; 70918-74-0; Piperazine, 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dihydro-1,4-Benzodioxin-2-Ylcarbonyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.